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Having an amphetamine-like chemical structurebupropion interferes with the assay used in some rapid urine drug screenswhich can result in false positive readingsparticularly for amphetaminesA positive result should usually be confirmed with a more specific method.

During pregnancythis medication should be used only when clearly neededBehavioral therapy and stop-smoking education is preferred for pregnant women who desire to stop smokingDiscuss the risks and benefits with your doctor.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some epidemiological studies of pregnancy outcomes following maternal exposure to bupropion in the first trimester have reported an association with increased risk of certain congenital cardiovascular malformations specifically ventricular septal defects and left outflow tract heart defectsThese findings are not consistent across studiesAnimal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicitysee section 5.3Zyban should not be used in pregnancyPregnant women should be encouraged to quit smoking without the use of pharmacotherapy.

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